Ruthin Town host Brickfield Rangers on Friday night in a game which will attract a lot of interest with it being the home side's new manager Colin Caton's first match in charge.
Former Bala Town boss Caton ended his 22-year reign with the Lakesiders in June and was recently appointed to lead Ruthin, where he was a player in the late 1980s and early 2000s.
Ruthin lie third from bottom of the Cymru North, with Brickfield four places above.
This game was due to be held last weekend, but got cancelled due to the weather.
ARDAL NORTH EAST
All seven matches in Tier 3 Ardal North East will be played on Saturday, with leaders Llanuwchllyn aiming to make it 13 unbeaten when they visit seventh-place Corwen.
As per usual, much focus will be on Llan's prolific striker Meilir Williams, North Wales senior football's current top-scorer with 24 league and cup goals.
Second-placed Knighton Town will be determined to build on last weekend's fine win at Cefn Albion when they host Rhos Aelwyd.
Bottom side Lex XI might fancy their chances of a first league win at the 13th attempt when they entertain a fourth from the basement Kerry outfit which has won just one of their last five.
At Cae Piod, Bow Street should have the measure of a visiting Llangollen Town still without a victory this term in 11 starts.
Third-place Penycae look a good shout to see off a third-from-bottom Builth Wells at Afoneitha Road, Cefn Albion might find things hard at Radnor Valley, while Llanrhaeadr will make it five straight wins if they get past visitors Llanfair United.
ARDAL NORTH WEST
On Friday evening, Prestatyn Town will aim to stretch their 100 percent home record to seven wins on the bounce when they welcome an improving bottom side St Asaph City to Bastion Gardens.
Asaph are coming off the back of their first league win of the campaign, a 2-0 success over Bethesda Athletic last weekend, so they travel to Prestatyn as far from no-hopers.
With top-two Porthmadog and CPD Dinas Bangor City 1876 on Welsh Cup duty, third-place Llangefni Town will look to close the gap on Saturday when they take on lowly Mynydd Isa at Cae Bob Parry.
Connah's Quay Town have a good chance to edge further away from the drop zone when they greet next-to-bottom Y Felinheli at Deeside Stadium.
With both Llannefydd and Bethesda Athletic having suffered disappointing results of late, it is hard to predict the outcome of their tussle at Cae Llannefydd.
The pair met recently in the Dragon Signs Amateur Trophy, Llan defeating Pesda 2-1 at home.
Another tricky one to call is Llay Welfare versus Penmaenmawr Phoenix. Third from bottom Pen have overcome a difficult start to the campaign by going unbeaten in their last five games - winning four - with the draw a 3-3 with high-flying Bangor where the visitors needed a penalty deep into added time to save their skins.
Llay are also on form, being undefeated in six matches.
NFA host Llanrwst United in another clash where both sides are notoriously hard to beat.
The Rwsters have not lost in six outings, while Rhyl-based NFA are renowned for being strong at home. A draw would not be a surprise result.
FIXTURES
JD CYMRU NORTH
Friday 21 November
Ruthin Town v Brickfield Rangers
LOCK STOCK ARDAL NORTH EAST
Saturday 22 November
Bow Street v Llangollen Town
Corwen v Llanuwchllyn
Knighton Town v CPD Rhos Aelwyd
Lex XI v Kerry
Llanrhaeadr v Llanfair United
Penycae v Builth Wells
Radnor Valley v Cefn Albion
LOCK STOCK ARDAL NORTH WEST
Friday 21 November
Prestatyn Town v St Asaph City
Saturday 22 November
Connah's Quay Town v CPD Y Felinheli
Llangefni Town v Mynydd Isa
CPD Llannefydd v Bethesda Athletic
Llay Welfare v Penmaenmawr Phoenix
NFA v Llanrwst United





